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All things Pharma

First oral contraception containing synthetic version of naturally occurring oestrogen made available

Gedeon Richter UK has announced the availability of Drovelis®▼(14.2mg estetrol [E4] plus 3mg drospirenone [DRSP]) as a combined oral contraceptive in the UK.1

The announcement comes approximately a year after the Medicines and Healthcare products Regulatory Agency (MHRA) granted a UK licence for E4/DRSP and means E4/DRSP is the first contraceptive tablet using this new combination of hormones (E4, an oestrogen, plus DRSP, a progestogen), to be made available by the NHS in England.1

Dr Diana Mansour, Consultant in Community Gynaecology and Reproductive Health Care, Newcastle upon Tyne, said: “Over three million women in the UK choose to take ‘the Pill’ as their main method of contraception. As healthcare professionals, we support increasing a patient’s contraceptive choice. For the first time, we are now able to prescribe a combined hormonal contraceptive tablet containing synthetic E4, plus the well-known progestogen DRSP.1,2

David Jordan, Medical Director UK and Ireland at Gedeon Richter said: “We have years of experience supporting women with their reproductive health and we are pleased to add this new combined oral contraceptive to our gynaecological portfolio.

“Choice plays an essential role when selecting a suitable contraceptive. We pride ourselves on being able to provide multiple options, across a number of delivery methods, and now including a combined hormonal tablet.”


1 MHRA. n.d. SPC – DROVELIS 3 MG/14.2 MG FILM-COATED TABLETS. Available at: https://mhraproducts4853.blob.core.windows.net/docs/4e8d612381da0bdcfaef7a19c788194a5dd8f6f6 Last accessed August 2022.

2 Iglikowski-Broad, V., 2021. Just a pill: 60 years of the contraceptive pill on the NHS. The National Archives blog. Available at: https://blog.nationalarchives.gov.uk/just-a-pill-60-years-of-the-contraceptive-pill-on-the-nhs/#:~:text=The%20pill%20has%20since%20been,million%20women%20taking%20it%2010. Last Accessed August 2022.

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